2021 Peter Mansfield Medal and Prize

Professor Brian F Hutton for distinguished contributions to the field of nuclear medicine, specifically in single-photon emission computed tomography quantification, image reconstruction and multimodality imaging, as well as for providing training in the field around the globe.

Professor Brian F Hutton IOP Peter Mansfield Medal and Prize winner 2021

Over his career, Professor Brian F Hutton has consistently pushed boundaries of what is achievable in nuclear medicine imaging in both imaging instrumentation and data processing.

He has continued to demonstrate remarkable insight to guide research in anticipation of developments that impact clinical practice, leading to innovation across a wide spectrum of topics. He is regularly invited to provide his perspective on current and future developments and contributes to international guidelines. Furthermore, he is recognised internationally as a gifted teacher.

His contributions to the field of nuclear medicine are significant.

Hutton is particularly recognised for his contribution to the development of accelerated maximum likelihood iterative reconstruction, for which he was co-recipient of the Institute of Electrical and Electronics Engineers’ Marie Sklodowska-Curie award and medal in 2014. This was key to bringing iterative reconstruction into daily practice for emission tomography; both positron emission tomography (PET) and single-photon emission computed tomography (SPECT).

He has initiated or contributed to a wide range of innovations in nuclear medicine, many of which have been applied across a range of clinical and research studies and are key to diagnostic and therapeutic accuracy, including:

  • the scanning line source for transmission scanning with SPECT adopted by several manufacturers prior to the introduction of SPECT/computerised tomography;
  • techniques for quantitative tomography including image registration, attenuation-based SPECT scatter correction, partial volume correction and motion correction;
  • algorithms for iterative reconstruction including resolution modelling, use of anatomical priors, and combined registration/reconstruction for automated alignment of emission and transmission data;
  • techniques for investigating lung disease with PET imaging, taking air and other tissue fractions into account;
  • novel SPECT instruments including the first clinical SPECT insert for simultaneous SPECT/magnetic resonance imaging currently undergoing evaluation prior to first in-human studies, and recently low-dose molecular breast imaging as well as evaluation of dedicated cadmium zinc telluride (CZT) cardiac SPECT and development of methods for dual radionuclide imaging for CZT; and
  • techniques that exploit the use of simultaneous PET/MRI including atlas-based attenuation correction, model-based motion correction and kinetic modelling without arterial sampling.

Hutton has also made significant contributions to the practice of nuclear medicine and the profession as a whole, including:

  • with the International Atomic Energy Agency, developing and managing a comprehensive distance assisted-training scheme for nuclear medicine professionals that has been adopted worldwide, especially in Asia and South America;
  • the development of standards for nuclear medicine instrumentation including through membership of the International Electrotechnical Commission working groups; and
  • initiation of the accreditation scheme for medical physicists in nuclear medicine through the Australasian College of Physical Scientists and Engineers in Medicine.