Stream Bio

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CPNs™ are derived from imaging polymers (semiconductors) found in OLED TV screens – it is these polymers that are at the core of Stream's nanoparticle. Current bioimaging technologies suffer from problems such as toxicity, poor brightness and fading after a couple of hours.

CPNs™ are significantly brighter than the current technologies available and haven’t shown any signs of fading after 12 months. 

The surface of the particle is designed to enable antibodies and other targetting agents to be fixed to it, which then allows the CPN™ to be directed at a specific target cell or protein. 

Stream has developed four colours (wavelengths) to target the life sciences R&D molecular probe market, specifically in cell labelling, imaging, tracking, disease diagnostics and drug development. A further four wavelengths are in the pipeline to allow scientists a greater choice to track multiple targets. 

The increased brightness enables a far greater sensitivity for detection, and within the polymer core and magnetic iron oxide particles, provide a cell purification capability not currently available. 

Looking beyond the R&D market for CPN™ molecular probes, research is being carried out to potentially use CPNs™ for improved medical diagnostics, fluorescence and MRI-guided surgery of tumours, and infrared imaging of tumours.

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