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Computational design and multiscale modeling of a nanoactuator using DNA actuation

Mustapha Hamdi 2009 Nanotechnology 20 485501 (9pp)   doi: 10.1088/0957-4484/20/48/485501  Help

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Mustapha Hamdi1
INRIA MICMAC, Ecole Nationale des Ponts et Chaussees, 6 and 8 avenue Blaise Pascal, Cite Descartes, Champs-sur-Marne, 77455 Marne La Vallee Cedex 2, France
1 Former address: PRISME institute, ENSI de Bourges, 88, Boulevard Lahitolle, 18020 Bourges Cedex, France
E-mail: hamdim@cermics.enpc.fr

Abstract. Developments in the field of nano-biodevices coupling nanostructures and biological components are of great interest in medical nanorobotics. As the fundamentals of bio/non-bio interaction processes are still poorly understood in the design of these devices, design tools and multiscale dynamics modeling approaches are necessary at the fabrication pre-project stage. This paper proposes a new concept of optimized carbon nanotube based servomotor design for drug delivery and biomolecular transport applications. The design of an encapsulated DNA-multi-walled carbon nanotube actuator is prototyped using multiscale modeling. The system is parametrized by using a quantum level approach and characterized by using a molecular dynamics simulation. Based on the analysis of the simulation results, a servo nanoactuator using ionic current feedback is simulated and analyzed for application as a drug delivery carrier.

Print publication: Issue 48 (2 December 2009)
Received 8 April 2009, in final form 31 August 2009
Published 30 October 2009

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