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Tracking nanoparticles in an optical microscope using caustics

Eann A Patterson et al 2008 Nanotechnology 19 105502 (7pp)   doi: 10.1088/0957-4484/19/10/105502  Help

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Eann A Patterson1 and Maurice P Whelan2
1 Department of Mechanical Engineering, Michigan State University, East Lansing, MI 48824, USA
2 Nanotechnology and Molecular Imaging Unit, Institute for Health and Consumer Protection, European Commission DG Joint Research Center, 21021 Ispra (VA), Italy

Abstract. An elegant method is proposed and demonstrated for tracking the location and movement of nanoparticles in an optical microscope using the optical phenomenon of caustics. A simple and reversible adjustment to the microscope generates caustics several orders of magnitude larger than the particles. The method offers a simple and relatively inexpensive method for visualizing such phenomena as the formation of self-assembled monolayers and the interaction of nanoparticles with chemically functionalized surfaces.

Print publication: Issue 10 (12 March 2008)
Received 24 September 2007, in final form 17 December 2007
Published 13 February 2008

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