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An integrated optical interferometric nanodevice based on silicon technology for biosensor applications

F Prieto et al 2003 Nanotechnology 14 907-912   doi: 10.1088/0957-4484/14/8/312  Help

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F Prieto1, B Sepúlveda1, A Calle1, A Llobera2, C Domínguez2, A Abad3, A Montoya3 and L M Lechuga1
1 Biosensors Group, Centro Nacional de Microelectrónica IMM-CNM, CSIC. Isaac Newton 8 (PTM), 28760 Tres Cantos, Madrid, Spain
2 Biosensors Group, Centro Nacional de Microelectrónica IMB-CNM, CSIC. Campus UAB, 08193 Bellaterra, Barcelona, Spain
3 Laboratorio Integrado de Bioingeniería, Universidad Politécnica de Valencia, Camino de Vera s/n, 46022 Valencia, Spain

Abstract. Integrated optical sensors have become important in recent years since they are the only technology which allows the direct detection of biomolecular interactions. Moreover, silicon microelectronics technology allows mass production as well as the fabrication of nano-/macrosystems on the same platform by hybrid integration of sources, sensors, photodetectors and complementary metal-oxide semiconductor electronics.

For the fabrication of an optical sensor nanodevice with an integrated Mach–Zehnder interferometric (MZI) configuration, the optical waveguides must have two main features: monomode behaviour and a high surface sensitivity. In this paper we present the development of a MZI sensor based on total internal reflection waveguides with nanometre dimensions. The aim is to use these sensors in environmental control to detect water pollutants by immunoassay techniques.

Print publication: Issue 8 (August 2003)
Received 7 October 2002, in final form 27 May 2003
Published 2 July 2003

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