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Analytical properties of time-of-flight PET data

Sanghee Cho et al 2008 Phys. Med. Biol. 53 2809-2821   doi: 10.1088/0031-9155/53/11/004  Help

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Sanghee Cho, Sangtae Ahn, Quanzheng Li and Richard M Leahy
Signal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089, USA
E-mail: leahy@sipi.usc.edu

Abstract. We investigate the analytical properties of time-of-flight (TOF) positron emission tomography (PET) sinograms, where the data are modeled as line integrals weighted by a spatially invariant TOF kernel. First, we investigate the Fourier transform properties of 2D TOF data and extend the 'bow-tie' property of the 2D Radon transform to the time-of-flight case. Second, we describe a new exact Fourier rebinning method, TOF-FOREX, based on the Fourier transform in the time-of-flight variable. We then combine TOF-FOREX rebinning with a direct extension of the projection slice theorem to TOF data, to perform fast 3D TOF PET image reconstruction. Finally, we illustrate these properties using simulated data.

For more information on this article, see medicalphysicsweb.org

Print publication: Issue 11 (7 June 2008)
Received 27 October 2007, in final form 21 February 2008
Published 6 May 2008

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