journals.iop.org home page electronic journals * User guide   * Site map   | Quick Search:Help  
Physics in Medicine and Biology
Athens/Institutional login
IOP login: Password:   
Create account | Alerts | Contact us
Journals Home | Journals List | EJs Extra | This Journal | Search | Authors | Referees | Librarians | User Options | Help |

Experimental spectral measurements of heavy K-edge filtered beams for x-ray computed mammotomography

D J Crotty et al 2007 Phys. Med. Biol. 52 603-616   doi: 10.1088/0031-9155/52/3/005  Help

   PDF (1.02 MB) | References | Articles citing this article

D J Crotty1,2, R L McKinley1,2 and M P Tornai1,2
1 Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
2 Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
E-mail: dominic.crotty@duke.edu

Abstract. A dual modality computed mammotomography (CmT) and single photon emission computed tomography (SPECT) system for dedicated 3D breast imaging is in development. Using heavy K-edge filtration, the CmT component narrows the energy spectrum of the cone-shaped x-ray beam incident on the patient's pendant, uncompressed breast. This quasi-monochromatic beam is expected to improve discrimination of tissue with similar attenuation coefficients while restraining absorbed dose to below that of dual view mammography. Previous simulation studies showed the optimal energy that maximizes dose efficiency for a 50/50% adipose/glandular breast is between 30 and 40 keV. This study experimentally validates these results using pre-breast and post-breast spectral measurements made under tungsten tube voltages between 40 and 100 kVp using filter materials with K-edge values ranging from 15 to 70 keV. Different filter material thicknesses are used, approximately equivalent to the 200th and 500th attenuating value layer (VL) thickness. Cerium (K = 40.4 keV) filtered post-breast spectra for 8–18 cm breasts are measured for a range of breast compositions. Figures of merit include mean beam energy, spectral full-width at tenth-maximum, beam hardening and dose for the range of breast sizes. Measurements corroborate simulation results, indicating that for a given dose, a 200th VL of cerium filtration may have optimal performance in the dedicated mammotomography paradigm.

Print publication: Issue 3 (7 February 2007)
Received 15 June 2006, in final form 28 November 2006
Published 10 January 2007

Bookmark and Share Post to CiteUlike | Post to Connotea | Post to Bibsonomy

 


Find related articles






Article options

Authors & Referees

 
Content finder
  Full Search
  Help


  
Setup information is available for Adobe Acrobat.
EndNote, ProCite ® and Reference Manager ® are registered trademarks of ISI Researchsoft.
Copyright © Institute of Physics and IOP Publishing Limited 2009.
Use of this service is subject to compliance with the Terms and Conditions of use. In particular, reselling and systematic downloading of files is prohibited.
Help: Cookies | Data Protection. Privacy policy Disclaimer