journals.iop.org home page electronic journals * User guide   * Site map   | Quick Search:Help  
Physics in Medicine and Biology
Athens/Institutional login
IOP login: Password:   
Create account | Alerts | Contact us
Journals Home | Journals List | EJs Extra | This Journal | Search | Authors | Referees | Librarians | User Options | Help |

Ion recombination correction in the Clatterbridge Centre of Oncology clinical proton beam

Hugo Palmans et al 2006 Phys. Med. Biol. 51 903-917   doi: 10.1088/0031-9155/51/4/010  Help

   PDF (331 KB) | References | Articles citing this article

Hugo Palmans1, Russell Thomas1 and Andrzej Kacperek2
1 National Physical Laboratory, Radiation Dosimetry Team, Teddington, TW11 0LW, UK
2 Clatterbridge Centre of Oncology, Douglas Cyclotron, Wirral, UK
E-mail: hugo.palmans@npl.co.uk

Abstract. Most codes of practice for dosimetry of proton beams do not give a clear recommendation on the determination of recombination correction factors for ionization chambers. In this work, recombination corrections were measured in the low-energy clinical proton beam of the Clatterbridge Centre of Oncology (CCO) using data collected at different dose rates and different polarizing voltages. This approach allows the separation of contributions from initial and volume recombination and was compared with results from extrapolation and two-voltage methods. A modified formulation of the method is presented for a modulated beam in which the ionization current is time dependent. Using a set-up with two identical chambers placed face-to-face yielded highly accurate data for plane-parallel ionization chambers. This method may also be used for high-energy photon and electron beam dosimetry. At typical dose rates of 26 Gy min−1 used clinically at the CCO, the recombination correction is 0.8% and thus is of importance for reference dosimetry. The proton beam should be treated as purely continuous given the high pulse repetition frequency of the cyclotron beam. The results show that the volume recombination parameter for protons is consistent with values measured for photon beams. Initial recombination was found to be independent of beam quality, except for a tendency to increase at the distal edge of the Bragg peak; this is only relevant for depth dose measurements. Using a general equation for recombination and generic values for the initial and volume recombination parameters (A = 0.25 V and m2 = 3.97 × 103 s cm−1 nC−1 V2), the experimental results are reproduced within 0.1% for all conditions met in this work. For the CCO beam and similar proton beams used for treating optical targets operating at high dose rates, the recombination correction factor can be overestimated by up to 2%, resulting in an overestimation of dose to water by the same amount, if the recommendation from IAEA TRS-398, which is only valid for pulsed beams, is followed without consideration.

Print publication: Issue 4 (21 February 2006)
Received 20 July 2005, in final form 6 December 2005
Published 1 February 2006

Bookmark and Share Post to CiteUlike | Post to Connotea | Post to Bibsonomy

 


Find related articles






Article options

Authors & Referees

 
Content finder
  Full Search
  Help


  
Setup information is available for Adobe Acrobat.
EndNote, ProCite ® and Reference Manager ® are registered trademarks of ISI Researchsoft.
Copyright © Institute of Physics and IOP Publishing Limited 2009.
Use of this service is subject to compliance with the terms and conditions of use. In particular, reselling and systematic downloading of files is prohibited.
Help: Cookies | Data Protection.