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REVIEW

Development of methods for body composition studies

Sören Mattsson et al 2006 Phys. Med. Biol. 51 R203-R228   doi: 10.1088/0031-9155/51/13/R13  Help

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Sören Mattsson1 and Brian J Thomas2
1 Department of Radiation Physics, Lund University, Malmö University Hospital, SE-205 02 Malmö, Sweden
2 School of Physical and Chemical Sciences, Queensland University of Technology, Brisbane, QLD 4001, Australia

Abstract. This review is focused on experimental methods for determination of the composition of the human body, its organs and tissues. It summarizes the development and current status of fat determinations from body density, total body water determinations through the dilution technique, whole and partial body potassium measurements for body cell mass estimates, in vivo neutron activation analysis for body protein measurements, dual-energy absorptiometry (DEXA), computed tomography (CT) and magnetic resonance imaging (MRI, fMRI) and spectroscopy (MRS) for body composition studies on tissue and organ levels, as well as single- and multiple-frequency bioimpedance (BIA) and anthropometry as simple easily available methods. Methods for trace element analysis in vivo are also described. Using this wide range of measurement methods, together with gradually improved body composition models, it is now possible to quantify a number of body components and follow their changes in health and disease.

Print publication: Issue 13 (7 July 2006)
Received 21 February 2006, in final form 29 March 2006
Published 20 June 2006

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